Daniel E. Winkowski

The paper integrates spatial multi-omics data from diffuse gliomas to identify locoregional metabolomic regulators linked to glioma growth and treatment resistance.

The paper develops and validates a CNS-specific library and analysis platform using the COMET(TM) system for high-dimensional proteomic multiplex imaging of the central nervous system.

The paper compares neuronal frequency preference and sound-level sensitivity in the primary auditory cortex of C57BL/6 and CBAxC57 F1 mice using in vivo 2-photon imaging.

This study shows that LRx in amblyopic mice induces MMP2/9 activity and ECM degradation in V1, enabling synaptic plasticity through homeostatic regulation of proteolysis.

This study examines neuronal activity in auditory cortex layers L4 and L2/3 of mice, finding that both spontaneous and evoked activity exhibit neuronal avalanches with similar power law distributions across sound levels.

The paper introduces a motion correction method for two-photon imaging of neuronal activity using particle tracking to compensate for movement artifacts in awake mice.