Ulrich H. von Andrian

The paper identifies MHC II-expressing bone marrow megakaryocytes as noncanonical antigen-presenting cells capable of activating CD4+ T cells and modulating immune responses.

immgenT creates a comprehensive T-cell molecular atlas across mouse organs and disease states, identifying 8 lineages and 107 clusters using deep generative models and integrating external datasets.

This study shows that nociceptors reprogram monocytes into immunosuppressive cells, hindering T cell-mediated tumor immunity in bladder cancer.

The paper identifies TCR-V gene usage patterns in T cells sorted by anti-TCR mAbs using single-cell RNAseq and finds enriched ERV1-family LTR expression in specific TRBV regions.

The paper examines T cell changes in mammary glands during pregnancy and lactation, finding an expansion of T effector cells and similarities to intestinal T cells.

This study identifies three distinct neutrophil subsets in the murine nasal mucosa with unique origins, phenotypes, and functions in immune surveillance.