Catarina C. F. Homem

This study identifies the Mediator complex as a key regulator of hypertranscription in Drosophila neural stem cells, showing its necessity for proper differentiation and stem cell fate.

FLYNC predicts long non-coding RNAs in Drosophila using machine learning, identifying novel tissue-specific lncRNAs and validating some via qPCR.

This study shows that rapid aPKC inactivation in Drosophila follicular epithelium causes tissue rupture through increased apical constriction, not polarity loss.

This study uses single-cell RNA sequencing and genetic strategies to analyze neuron maturation in Drosophila, showing that maturation begins post-neuron birth through transcriptional changes coordinated with developmental stage.