Mariana Osswald

This study shows that elevated MPS1 causes chromosomal instability in colon cancer by converting the fibrous corona into a source of merotelic kinetochore-microtubule attachments.

The paper identifies RhoGAP15B as a spatial inhibitor of RhoA that promotes protrusive activity during collective cell migration in Drosophila border cells.

The paper identifies Dystrophin-Dystroglycan as essential for cytokinesis efficiency in Drosophila epithelia by regulating ring contraction and preventing membrane regression.

This study shows that rapid aPKC inactivation in Drosophila follicular epithelium causes tissue rupture through increased apical constriction, not polarity loss.

This study reveals how substrate-induced clustering activates TRIM21's ubiquitination activity for antiviral responses and protein degradation, introducing optogenetically controllable TRIM21-nanobody chimeras.