Author

André Barros-Carvalho

Universidade do PortoORCID 0000-0001-6039-2956Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:Drosophila· 3 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Eurico Morais‐de‐SáiD· 3 shared Mariana OsswaldiD· 2 shared Ana M. Carmo· 1 shared Cai T. Johnson· 1 shared Catarina C. F. HomemiD· 1 shared Christopher P. EarliD· 1 shared Cláudio E. SunkeliD· 1 shared Colin NixoniD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersDevelopmental Biology

Eurico Morais‐de‐SáORCID

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4 papers

Recent·Most cited

Developmental BiologybioRxivPreprintApr 16, 2025

Biomechanical Compartmentalisation Influences Angiogenesis and Stem Cell Proliferation in the Regenerating Intestine via Vascular Piezo.

Jade A. Phillips, Jessica Perochon, Cai T. Johnson…·Julia B. Cordero

This study identifies biomechanical compartmentalization in the regenerating intestine and shows vascular Piezo1 influences angiogenesis and stem cell proliferation across species.

1 citation

Drosophilamouse

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BiochemistryNature Structural & Molecular BiologyPeer-reviewedJan 6, 2025

Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multi-site polarity substrate Lgl

Christopher P. Earl, Mathias Cobbaut, André Barros-Carvalho…·Neil Q. McDonald

The paper reports the structure of aPKC-Par6 bound to Lgl1 and proposes a model for its mutual inhibition and release mechanism in cell polarity.

12 citations

humanexperimental assay

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Developmental BiologyCurrent BiologyPeer-reviewedSep 15, 2022

Apical constriction induces tissue rupture in a proliferative epithelium

Mariana Osswald, André Barros-Carvalho, Ana M. Carmo…·Eurico Morais‐de‐Sá

This study shows that rapid aPKC inactivation in Drosophila follicular epithelium causes tissue rupture through increased apical constriction, not polarity loss.

32 citations

Drosophilaexperimental assay

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Developmental BiologyDevelopmentPeer-reviewedJul 14, 2020

Lgl cortical dynamics are independent of binding to the Scrib-Dlg complex but require Dlg-dependent restriction of aPKC

Guilherme Ventura, Sofia Moreira, André Barros-Carvalho…·Eurico Morais‐de‐Sá

22 citations

Drosophilaexperimental assay

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