James W. Smyth

This study investigates how mild traumatic brain injury (TBI) alters connexin43 (Cx43) phosphorylation in astrocytes and how this contributes to seizure susceptibility in mice.

This paper optimizes a protocol for isolating murine BBB capillaries and evaluates its effectiveness in reducing non-vascular and non-capillary material.

This paper develops an inducible Vhl knockout mouse model to study chronic hypoxic stress in cardiomyocytes, revealing early gene expression changes linked to cardiac remodeling and disease.

This study shows that Cx43 and its isoform GJA1-20k facilitate mitochondrial transfer from mesenchymal stromal cells to chondrocytes, particularly under oxidative stress, suggesting potential therapeutic applications for osteoarthritis.