Author

Isabella Angela Iasenza

Research Institute of the McGill University Health CentreORCID 0000-0003-4254-5386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea L. Neumann· 2 shared Hassan DakikiD· 2 shared Josée HébertiD· 2 shared Kolja EppertiD· 2 shared Manon SabyiD· 2 shared Meaghan BoileauiD· 2 shared Patricia Arreba-Tutusaus· 2 shared Bahareh Jafari· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

Andrea L. Neumann

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 15, 2026

Glucocorticoids reprogram human AML leukemic stem cells to promote elimination through differentiation and apoptosis

Isabella Angela Iasenza, Yi Ling Sun, LeRon Best…·Kolja Eppert

This study shows glucocorticoids eliminate AML leukemic stem cells by inducing differentiation and apoptosis, with mechanisms involving the glucocorticoid receptor and inflammatory signatures.

DOI 10.64898/2026.09.09.750191

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 10, 2026

Discovery of compounds targeting human acute myeloid leukemia stem cells via a novel high-throughput screen

Isabella Angela Iasenza, Safia Safa-Tahar-Henni, Hassan Dakik…·Kolja Eppert

This study identifies compounds targeting human AML stem cells through a high-throughput screen and validates their efficacy using xenotransplantation and single-cell RNA sequencing.

DOI 10.64898/2026.09.09.750169

humanbulk RNA-seq

𝕏 PostBluesky