Author

Josephine G. M. Strijker

Princess Máxima CenterORCID 0000-0003-4260-2942Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Elisavet Kalaitsidou· 2 shared Jan J. MolenaariD· 2 shared John AndersoniD· 2 shared Judith WienkeiD· 2 shared Wei WuiD· 2 shared Arjan BoltjesiD· 1 shared Brendan C. McIntyreiD· 1 shared Chunlong ZhaoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Elisavet Kalaitsidou

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 3, 2025

Proteomic profiling of the neuroblastoma secretome identifies extracellular vesicles as drivers of T cell suppression

Josephine G. M. Strijker, Ronja E. van Berkum, Elisavet Kalaitsidou…·Judith Wienke

The paper identifies extracellular vesicles as immunosuppressive factors in neuroblastoma by profiling secretomes and showing their ability to suppress T cell activation.

DOI 10.64898/2025.12.02.690421

humanproteomics

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Cancer BiologyEuropean Journal of CancerPeer-reviewedJan 27, 2025

Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma

Josephine G. M. Strijker, Guillem Pascual‐Pasto, Grant P. Grothusen…·Judith Wienke

This study identifies MIF as a key immunosuppressive factor in neuroblastoma that inhibits CAR T-cell efficacy, showing that blocking MIF enhances T-cell activation and therapeutic potential.

25 citationstop 1%

humanbulk RNA-seq

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