Author

Grant P. Grothusen

Children's Hospital of PhiladelphiaORCID 0000-0001-9236-0369Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Brendan C. McIntyreiD· 1 shared Chunlong ZhaoiD· 1 shared Courtney HimsworthiD· 1 shared Elisavet Kalaitsidou· 1 shared Frank J. DekkeriD· 1 shared Guillem Pascual‐PastoiD· 1 shared Henrike P. MulleriD· 1 shared Jan J. MolenaariD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Brendan C. McIntyreORCID

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1 paper

Recent·Most cited

Cancer BiologyEuropean Journal of CancerPeer-reviewedJan 27, 2025

Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma

Josephine G. M. Strijker, Guillem Pascual‐Pasto, Grant P. Grothusen…·Judith Wienke

This study identifies MIF as a key immunosuppressive factor in neuroblastoma that inhibits CAR T-cell efficacy, showing that blocking MIF enhances T-cell activation and therapeutic potential.

25 citationstop 1%

humanbulk RNA-seq

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