Leidy D. Caraballo Galva

This study shows that IL-18 enhances antitumor activity of CAR-NKT cells against neuroblastoma by promoting metabolic reprogramming and reducing exhaustion markers.

The paper introduces a library of inducible split recombinases for precise and multiplexed gene expression control in mammalian cells and mice.

This paper introduces gene circuits with memory to control gene expression in T cells, demonstrating regulation of CAR expression and T cell activity using an FDA-approved drug.