Author

Jiayi Hu

City University of Hong KongORCID 0000-0003-4263-9454Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Haowen LiuiD· 2 shared Jiafan WangiD· 2 shared Jingyao XiaiD· 2 shared Lei LiiD· 2 shared Zhitao HuiD· 2 shared Bei WangiD· 1 shared Chun HaniD· 1 shared Cong MaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Haowen LiuORCID

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3 papers

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJun 18, 2026

Evolutionarily Conserved and Divergent Mechanisms of Dual Ca2+ Sensors in Synaptic Vesicle Exocytosis

Lei Li, Jiafan Wang, Jingyao Xia…·Zhitao Hu

This study investigates how SNT-1 and SNT-3 mediate fast and slow neurotransmitter release in C. elegans by analyzing their interactions with SNARE complexes and polybasic motifs.

DOI 10.1073/pnas.2532992123

C. elegansproteomics

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NeuroscienceeLifePeer-reviewedApr 11, 2025

Mechanisms that regulate the C1-C2B mutual inhibition controls functional switch of UNC-13

Haowen Liu, Lei Li, Jiafan Wang…·Zhitao Hu

This study identifies a mechanism by which UNC-13 in C. elegans regulates synaptic vesicle exocytosis through domain interactions and functional switches.

DOI 10.7554/elife.105199

C. elegansexperimental assay

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NeurosciencebioRxivPreprintSep 25, 2023

Tissue-specific knockout in Drosophila neuromuscular system reveals ESCRT's role in formation of synapse-derived extracellular vesicles

Xinchen Chen, Sarah Perry, Bei Wang…·Chun Han

The paper develops a CRISPR toolkit for tissue-specific gene knockout in Drosophila motor neurons, muscles, and glial cells, revealing ESCRT's role in NMJ extracellular vesicle formation.

DOI 10.1101/2023.09.25.559303

Drosophilaexperimental assay

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