Author

Prasun Kumar

University of BristolORCID 0000-0002-2008-3347Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Prasun Kumar1 paper

Biology Disciplines

Click to filter author papers

Bioinformatics· 2 Biochemistry· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:protein structure· 3 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Derek N. WoolfsoniD· 3 shared Emmanuel D. LevyiD· 2 shared Hugo SchwekeiD· 2 shared Afreen HaqueiD· 1 shared Anna Rose AntonyiD· 1 shared Benjamin DubreuiliD· 1 shared Bruno E. CorreiaiD· 1 shared Casper A. GoverdeiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioinformatics

Derek N. WoolfsonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

IKK2/β mediated phosphorylation of transcription factor Ets2 at site(s) distal to DNA binding domain negatively modulates its DNA binding activity

Deeparna Sutradhar, Anna Rose Antony, Afreen Haque, Prateeka Borar, Pallavi T Rao, Swasti Raychaudhuri, Prasun Kumar, Smarajit Polley

The paper identifies S295 as a phosphorylation site on Ets2 regulated by IKK2/β, showing that phosphorylation inhibits DNA binding activity.

bioRxiv · Sep 1, 2026 · PreprintBiochemistry

An atlas of protein homo-oligomerization across domains of life

Hugo Schweke, Martin Pačesa, Tal Levin, Casper A. Goverde, Prasun Kumar, Yoan Duhoo, L Dornfeld, Benjamin Dubreuil, Sandrine Georgeon, Sergey Ovchinnikov, Derek N. Woolfson, Bruno E. Correia, Sucharita Dey, Emmanuel D. Levy

The paper predicts homo-oligomerization across four proteomes using AlphaFold2, finding that 50% of archaea, 45% of bacteria, and 20% of eukaryotes form homomers, with disease mutations enriched at interfaces.

Cell · Feb 1, 2024Peer-reviewedBioinformatics

CC + : A Searchable Database of Validated Coiled coils in PDB Structures and AlphaFold2 Models

Prasun Kumar, Rokas Petrenas, William Dawson, Hugo Schweke, Emmanuel D. Levy, Derek N. Woolfson

The paper updates a database of coiled-coil structures from experimental data and AlphaFold2 models, enabling searches and analysis of coiled-coil assemblies and their sequence-structure relationships.

Protein Science · Sep 28, 2023Peer-reviewedBioinformatics

Constructing synthetic-protein assemblies from de novo designed 310 helices

Prasun Kumar, Neil G. Paterson, Jonathan Clayden, Derek N. Woolfson

This paper designs and characterizes synthetic protein assemblies composed of 310 helices, demonstrating their ability to form stable structures despite their rarity in natural proteins.

bioRxiv · Dec 11, 2021 · PreprintSynthetic Biology