Maciej Sikora

This study uses single-molecule force spectroscopy and molecular dynamics to analyze the unfolding and folding of double-knotted and single-knotted proteins, revealing that double-knotted proteins require chaperone assistance for full knotting.

This study uses machine learning to predict protein knotting from amino acid sequences, achieving 98.5% accuracy using AlphaFold predictions and UniProt data.