Klaus T. Wanner

This paper synthesizes and evaluates nipecotic acid derivatives with allenic spacers as mGAT4 inhibitors, identifying a potent compound with anticonvulsant and anxiolytic effects in mice.

This paper identifies novel ligands binding to MB327-PAM-1, a binding site for resensitizing nAChRs, including cycloguanil, which shows higher affinity and functional efficacy.

This study synthesizes and evaluates new MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after nerve agent intoxication, identifying more potent compounds than MB327.