Thomas W. Glover

The paper identifies a phospho-switch mechanism that reprograms TRAIP to ubiquitylate replisomes in mitosis, enabling disassembly of unreplicated DNA.

HiFiRe3 improves rare structural variant detection by reducing artifacts through error suppression and correction strategies across long and short-read sequencing platforms.

The paper investigates SV formation at common fragile sites during mitosis and identifies POLQ-mediated end-joining as a key mechanism.

The paper introduces svCapture, a method for detecting rare structural variant junctions with high accuracy using error-minimized capture sequencing.