Author

Gavin K. Hanson

Case Western Reserve UniversityORCID 0000-0003-4427-599XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:Ribo-seq· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Jeff M. ColleriD· 2 shared Thomas J. SweetiD· 2 shared Ashrut NarulaiD· 1 shared Daniel ArangoiD· 1 shared James EllisiD· 1 shared Megan E. ForrestiD· 1 shared Najwa AlhusainiiD· 1 shared Nathan J. MorrisiD· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Jeff M. CollerORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 7, 2018

Codon usage and amino acid identity are major determinants of mRNA stability in humans

Megan E. Forrest, Ashrut Narula, Thomas J. Sweet…·Olivia S. Rissland

The paper shows that codon usage and amino acid identity significantly influence mRNA stability in humans, affecting protein abundance through translational elongation rates.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyRNAPeer-reviewedJul 11, 2018

Translation elongation and mRNA stability are coupled through the ribosomal A-site

Gavin K. Hanson, Najwa Alhusaini, Nathan J. Morris…·Jeff M. Coller

The paper shows that faster translation elongation on optimal codons increases mRNA stability in yeast, with A-site tRNA decoding being the key factor driving mRNA decay.

49 citations

yeastRibo-seq

𝕏 PostBluesky