Molecular BiologyRNAPeer-reviewed
Translation elongation and mRNA stability are coupled through the ribosomal A-site
Gavin K. Hanson, Najwa Alhusaini, Nathan J. Morris…·Jeff M. Coller
The paper shows that faster translation elongation on optimal codons increases mRNA stability in yeast, with A-site tRNA decoding being the key factor driving mRNA decay.