Panos Z. Anastasiadis

This study identifies therapeutic options, biomarkers, and resistance mechanisms for high-grade gliomas using genomic, transcriptomic profiling, and drug testing in patient-derived models.

This study shows that Plekha7 maintains retinal organization by regulating cadherin trafficking and epithelial structure, and its loss leads to inflammation and photoreceptor loss.

The paper investigates the functional impact of the HyperDuplication GenomoPhenotype in high copy number endometrial cancer, showing it enhances tumor fitness and therapy resistance through coordinated duplication of oncogenes.

The paper identifies a potent MET degrader using live cell imaging, showing it is more effective than existing PROTACs.