Author

Carla Calagua

Beth Israel Deaconess Medical CenterORCID 0000-0003-4438-8046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

David Johnson EinsteiniD· 2 shared Olga S. VoznesenskyiD· 2 shared Seifeldin AwadiD· 2 shared Steven P. BalkiD· 2 shared Adam G. SowalskyiD· 1 shared Alex TokeriD· 1 shared Anson T. KuiD· 1 shared Betul Ersoy-FazliogluiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

David Johnson EinsteinORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 30, 2026

Higher T-cell density in primary prostate cancer is associated with reduced fraction of CD8 effector cells and increased TIGIT

Seifeldin Awad, Carla Calagua, Olga S. Voznesensky…·Steven P. Balk

The paper examines immune infiltration in prostate cancer, finding higher T-cell density correlates with reduced CD8 effector cells and increased TIGIT, suggesting immune suppression.

DOI 10.64898/2026.08.27.747524

humanbulk RNA-seq

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Cancer BiologyJournal of Clinical InvestigationPeer-reviewedOct 2, 2025

Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion

Fen Ma, Sen Chen, Luigi Giovanni Cecchi…·Steven P. Balk

This study shows that in prostate cancer with TMPRSS2:ERG fusion, androgen deprivation increases AKT activation, which may reduce the effectiveness of AR-targeted therapy, suggesting combination therapy could be beneficial.

4 citations

mousehuman

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