Yong-Woo Kim

This paper introduces a gene replacement tool called Prime Assembly (PA) that efficiently and accurately replaces large DNA fragments in human cells, restoring gene function in disease-related genes.

This paper introduces a method using virus-like particles to enable orthogonal genome editing by packaging distinct CRISPR effectors and gRNAs, allowing simultaneous gene editing without gRNA crosstalk in vitro and in vivo.

This paper introduces snuABE, a single-nucleotide resolution ABE that reduces bystander effects through engineered ADAR and tagRNA design, achieving precise A-to-G editing in human cells.