Author

Shuo Zhang

University of PennsylvaniaORCID 0000-0003-4496-3661Unclaimed ORCID profile · follow to get notified of new preprints

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Shuo Zhang5 papers · University of Pennsylvania

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

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Benjamin L. ProsseriD· 1 shared Beverly L. DavidsoniD· 1 shared Deborah L. FrenchiD· 1 shared Elisa A. WaxmaniD· 1 shared Elizabeth A. HelleriD· 1 shared Giulia PavaniiD· 1 shared Ingie HongiD· 1 shared Julia J. WinteriD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Benjamin L. ProsserORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintOct 28, 2025

CRISPR-mediated transcriptional activation as a mutation-independent therapeutic strategy for SYNGAP1-related intellectual disability

Laura Sichlinger, Molly B. Reilly, Sakshi Arora…·Elizabeth A. Heller

This paper demonstrates that CRISPR-mediated transcriptional activation can upregulate SYNGAP1 in a mouse model of SRID and human neurons, rescuing deficits without targeting mutations.

3 citations

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