Author

Avinaash K. Sandhu

University Hospitals of ClevelandORCID 0000-0003-4501-1478Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Daniel P. GailiD· 2 shared Stephen M. CarpenteriD· 2 shared Alessandro SetteiD· 1 shared Bryan D. BrysoniD· 1 shared Cecilia S. Lindestam ArlehamniD· 1 shared Charles Bark· 1 shared Demetria Webb· 1 shared Laura Hmiel· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Daniel P. GailORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 10, 2026

Restricted MHC-II trafficking in Mycobacterium tuberculosis-infected M2-like macrophages limits CD4+ T cell activation

Avinaash K. Sandhu, Daniel P. Gail, Rachel C. Simmermon…·Stephen M. Carpenter

This study identifies IL-10 and type I IFN signaling as mechanisms that restrict MHC-II trafficking in Mtb-infected M2-like macrophages, limiting CD4+ T cell activation.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 23, 2025

Human memory CD4+ T cells recognize Mycobacterium tuberculosis-infected macrophages amid broader pathogen-specific responses

Volodymyr Stetsenko, Daniel P. Gail, Scott M. Reba…·Stephen M. Carpenter

The paper shows that most Mtb-specific CD4+ T cells from LTBI individuals recognize infected macrophages, but some require exogenous antigen, and identifies effector functions associated with TB protection.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky