Yingxue Ren

This study identifies cholesterol dependency as a therapeutic target in glioblastoma, showing that combined treatment with clemastine and bexarotene induces metabolic collapse and enhances antitumor immunity.

This study uses single-cell multi-omics data to identify disrupted glial gene regulatory programs in Alzheimer's disease using interpretable machine learning.

This study develops a PD-L1-targeting CAR T cell therapy, MC9999, which effectively eradicates glioblastoma and immunosuppressive cells in the tumor microenvironment through intracranial delivery.

The paper identifies miR-29 and ATG9A as regulators of mitophagy and discovers EOPD-linked variants in ATG9A.

The paper identifies four genes, including two novel ones, co-expressed with TREM2 in Alzheimer's disease using whole-exome data from ADSP.

The paper describes a Swift/T wrapper for the GATK variant calling workflow to improve portability and maintainability across cluster environments.