Author

Nicholas T. Thomas

University of KentuckyORCID 0000-0003-4578-8463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Yuan WeniD· 3 shared Christopher S. FryiD· 2 shared Kevin A. MurachiD· 2 shared Ahmed IsmaeeliD· 1 shared Björn A. AlkneriD· 1 shared Calvin S. Peterson· 1 shared Carla MC NascimentoiD· 1 shared Charlotte A. PetersoniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Yuan WenORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 27, 2026

Skeletal Muscle Stem Cell-Derived Myonuclei Adopt Divergent Terminal Transcriptional States in Adult and Aged Muscle In Response to a Hypertrophic Stimulus

Nicholas T. Thomas, Jensen Z. Goh, Kevin A. Murach…·Yuan Wen

The paper identifies age-related differences in the transcriptional states of MuSC-derived myonuclei in response to mechanical overload.

DOI 10.64898/2026.08.26.747125

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PhysiologyAmerican Journal of Physiology-Cell PhysiologyPeer-reviewedNov 12, 2025

Pediatric CHOP Chemotherapy Acutely Disrupts Satellite-Cell Dynamics and Blunts Muscle Mass in a Sex-Specific Manner

Jainil Daredia, Marc A Magaña, Carla MC Nascimento…·Michael P. Wiggs

2 citations

mousebulk RNA-seq

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Cell BiologyEMBO ReportsPeer-reviewedOct 31, 2024

The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator That is Sufficient for Growth

Sebastian Edman, Ronald G. Jones, Paulo R. Jannig…·Ferdinand von Walden

This study maps the 24-hour molecular response to resistance exercise in human muscle, identifying MYC as a key regulator of hypertrophy and mRNA levels.

44 citationstop 3%

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