Author

Shi Quan Wong

Brown UniversityORCID 0000-0003-4597-3001Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Louis R. LapierreiD· 2 shared Acacia Nawrocik-MadridiD· 1 shared Adia Ouellette· 1 shared Alexander Alexandrov· 1 shared Arturo AndradeiD· 1 shared Avery McNamara· 1 shared Brett C. GinsburgiD· 1 shared Catherine J Ryan· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Louis R. LapierreORCID

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2 papers

Recent·Most cited

NeuroscienceGeroSciencePeer-reviewedFeb 6, 2026

Spatial memory in Alzheimer's disease 5XFAD mice is enhanced by XPO1 inhibitor KPT-330

Shi Quan Wong, Adia Ouellette, Laura Harrison…·Louis R. Lapierre

This study shows that XPO1 inhibitor KPT-330 improves spatial memory in Alzheimer's 5XFAD mice by reducing amyloid deposition in specific brain regions while increasing overall amyloid levels.

3 citationstop 4%

mouseproteomics

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GeneticsbioRxivPreprintApr 7, 2022

Neuronal HLH-30/TFEB modulates muscle mitochondrial fragmentation to improve thermoresistance in C. elegans

Shi Quan Wong, Catherine J Ryan, Louis R. Lapierre

This study shows neuronal HLH-30/TFEB improves thermoresistance in C. elegans by inducing mitochondrial fragmentation in muscles, independent of DAF-16/FOXO.

1 citation

C. elegansstatistical model

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