Author

Federica Vecchio

Centre National de la Recherche ScientifiqueORCID 0000-0003-4607-8818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Roberto MalloneiD· 2 shared Alexia CarréiD· 1 shared Amelia K. LinnemanniD· 1 shared Annalisa NicastriiD· 1 shared Barbara BrandaoiD· 1 shared Chloe M. ShepherdiD· 1 shared Clémentine HallieziD· 1 shared Decio Laks EizirikiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Roberto MalloneORCID

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2 papers

Recent·Most cited

ImmunologyScience AdvancesPeer-reviewedJun 19, 2026

Coxsackievirus B Escapes Antiviral CD8⁺ T Cells but Triggers Robust CD4⁺ Memory Responses

Orlando Burgos Morales, Federica Vecchio, Fatoumata Samassa…·Roberto Mallone

This study shows that Coxsackievirus B3 evades CD8+ T-cell immunity by downregulating HLA Class I and viral peptide presentation, while inducing robust CD4+ T-cell responses and memory formation.

1 citation

humanproteomics

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Molecular BiologyNature CommunicationsPeer-reviewedOct 26, 2022

The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α

Vikash Chandra, Hazem Ibrahim, Clémentine Halliez…·Timo Otonkoski

This study shows that TYK2 is critical for β-cell development by regulating KRAS and IFN responses, suggesting TYK2 inhibition as a therapeutic target for type 1 diabetes.

55 citationstop 2%

humanbulk RNA-seq

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