Gayane Hovhannisyan

This study identifies PTPRF as a stress-responsive cytoskeletal checkpoint that coordinates metabolic adaptation in hepatocytes and β cells by linking metabolic stress to actin reorganization.

This study shows Rhpn2 promotes zebrafish melanoma development and aggressiveness by enhancing tumor growth and invasion.

CellCousin2 improves lineage tracing in zebrafish by reducing background recombination and enhancing ablation efficiency with a new system.

This study shows that loss of PTPRK in hepatocytes reduces steatosis and tumour development in obesity-induced hepatocellular carcinoma.

This study shows that cholangiocytes generate new hepatocytes during zebrafish liver regeneration after partial injury during growth.

This study identifies PTPRK's role in promoting hepatocyte metabolic reprogramming in obesity by regulating glycolysis and lipogenesis, with potential therapeutic implications for obesity-related liver diseases.