Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics
Rebecca J. Carlson, J. J. Patten, George Stefanakis, Brian Y. Soong, Adityanarayanan Radhakrishnan, Avtar K Singh, Naveen Thakur, Kathleen C. F. Sheehan, Gaya K. Amarasinghe, Nir Hacohen, Christopher F. Basler, Daisy W. Leung, Caroline Uhler, Robert A. Davey, Paul C. Blainey
This study uses single-cell image-based CRISPR screens to identify host factors regulating Ebola virus infection, revealing new therapeutic targets like UQCRB and STRAP.
Nature Microbiology · Jul 24, 2025Peer-reviewedMicrobiology