Author

Caiming Wu

Xiamen UniversityORCID 0000-0003-4750-783XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ailing Zou· 1 shared Baoding ZhangiD· 1 shared Hanqi LiuiD· 1 shared Hongrui WangiD· 1 shared Hui CaoiD· 1 shared Ji Li· 1 shared Jie Ouyang· 1 shared Jie YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Ailing Zou

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2 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedMar 1, 2026

FASN Inactivation-induced Progranulin (GRN) Expression Promotes Lysosome-dependent Cell Death to Suppress Leukemogenesis

Meng Su, Qinglin Li, Zhiyi Lv…·Yang Mei

This study shows that inhibiting FASN leads to lysosome-dependent cell death via GRN expression, suppressing leukemogenesis in myeloid leukemia.

1 citation

mouseexperimental assay

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Cancer BiologyActa Pharmaceutica Sinica BPeer-reviewedJul 25, 2025

Targeting oncogenic K-Ras mutants with a small-molecule degrader through Nedd4-1

Taoling Zeng, Tingting Jiang, Baoding Zhang…·Hongrui Wang

This study develops a small-molecule degrader, XMU-MP-9, that promotes ubiquitination and degradation of K-Ras mutants, including K-RasG12V, by enhancing Nedd4-1 interaction with K-Ras.

4 citations

humanproteomics

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