Steffen B. E. Wolff

Neurobehavioral effects of focused ultrasound-mediated blood-brain barrier opening

This study evaluates the neurobehavioral effects of MB-FUS in rats, showing dose- and target-dependent adverse effects on behavior and brain tissue.

Rapid modeling of an ultra-rare epilepsy patient variant in mice by in utero prime editing

This paper describes a method to rapidly create mouse models of human epilepsy variants using in utero prime editing, enabling the study of seizures in a clinically relevant timeframe.

Long-term stability of single neuron activity in the motor system

This study records single neuron activity in motor cortex and striatum over weeks in rats performing motor behaviors, finding long-term stability in activity patterns despite minor drift.

The basal ganglia can control learned motor sequences independently of motor cortex

This study shows that the basal ganglia, specifically the striatum, control learned motor sequences independently of the motor cortex in rats.

Encoding of 3D Head Orienting Movements in Primary Visual Cortex

This study shows that 3D head orienting movements modulate V1 neuronal activity in a direction-specific manner, with two distinct populations of neurons responding in light and dark conditions.

Distinct roles for motor cortical and thalamic inputs to striatum during motor learning and execution

This study investigates the roles of motor cortical and thalamic inputs to the striatum during motor learning and execution in rats, finding that cortical input is critical for learning but not execution, while thalamic input is essential for maintaining learned behavior.