Andrea J. Romanowski

This study maps the cortical inputs to the inferior pulvinar in marmosets, revealing its role as a central integrative node in visual and visuomotor networks.

The paper uses stereo-tracking to study Purkinje cell development and identifies a new subcellular structure called axon bubbles.

The paper identifies topographic principles in the corpus callosum that guide axon connectivity between brain hemispheres through symmetric adhesion molecule levels and co-fasciculation.

This paper describes a method to rapidly create mouse models of human epilepsy variants using in utero prime editing, enabling the study of seizures in a clinically relevant timeframe.

The paper develops a high-throughput workflow to assess Cas9 editing precision and identifies a novel Cas9 fusion that improves knockin performance in vivo.

The paper investigates NPRL3 variants' effects on mTOR signaling, cortical development, and epilepsy by using CRISPR/Cas9 knockout in cell lines and mice, showing mTOR hyperactivation and cortical dyslamination.