Michael J. Sherratt

This study compares circadian rhythms in photoprotected and photoexposed human skin, finding reduced rhythmic genes and advanced peak times in sun-exposed skin.

This paper introduces TomoSAXS to map fibril-to-fibre mechanics in intervertebral discs and shows how pre-strain and strain variability correlate with mechanical behavior.

The paper uses peptide location fingerprinting to identify age- and disease-related structural changes in proteins across species and tissues.

The paper identifies age-related biomarkers in human skin and tendon proteomes using peptide location fingerprinting and a new webtool.

The paper develops a deep learning model to predict protein degradation by proteases and UVR/ROS in human skin, validated against experimental data and integrated into a web tool for proteome susceptibility analysis.

This study examines how aging and estrogen deficiency affect skin matrix composition and mechanics in mice, finding contrasting effects on tensile strength and collagen levels.