Author

Hongzhu Ji

Howard Hughes Medical InstituteORCID 0000-0003-4760-8526Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Oliver HobertiD· 3 shared Berta Vidal· 2 shared Chien‐Po LiaoiD· 2 shared Christopher M. Fang-YeniD· 1 shared Elisabeth A. Conklin· 1 shared G. Robert AguilariD· 1 shared Giulio ValpergaiD· 1 shared Hongfei JiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Oliver HobertORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 11, 2026

Genome-engineered C. elegans strains with sex-transformed neurons and gut

Chien‐Po Liao, Hongzhu Ji, Oliver Hobert

The paper describes CRISPR/Cas9-engineered C. elegans strains with tissue-specific sex transformations and validates their effects through gene expression and behavioral analysis.

DOI 10.64898/2026.10.04.756053

C. elegansexperimental assay

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Developmental BiologybioRxivPreprintJul 1, 2026

Regulatory architecture controlling terminal differentiation of an interoceptive paraneuron in C. elegans

Hongzhu Ji, Berta Vidal, Elisabeth A. Conklin…·Oliver Hobert

The paper identifies transcriptional programs controlling terminal differentiation of uv1 paraneurons in C. elegans, revealing shared regulatory mechanisms with canonical neurons.

DOI 10.64898/2026.05.28.728471

C. elegansChIP-seq

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NeurosciencePLoS BiologyPeer-reviewedJan 6, 2025

Functional analysis of conserved C. elegans bHLH family members uncovers lifespan control by a peptidergic hub neuron

G. Robert Aguilar, Berta Vidal, Hongzhu Ji…·Oliver Hobert

The paper identifies the role of C. elegans bHLH genes in specifying neuron identity and function, revealing that hlh-15/NHLH controls lifespan through neuropeptide secretion in AVK neurons.

8 citations

C. elegansstatistical model

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