Jia Guo

This study shows that disrupting SORL1-retromer recycling in mice leads to age-dependent brain atrophy resembling Alzheimer's disease, which can be reversed by restoring SORL1 function.

This study shows that IDH1-mutant glioma cells are more sensitive to cysteine-methionine deprivation and ferroptosis inducers, and that IDH inhibitors enhance this sensitivity.

This study shows lower hemoglobin levels increase hematoma expansion and poor outcomes in intracerebral hemorrhage using human data and a mouse model.

This paper introduces a deep learning approach for spectral registration in MRS data, showing improved accuracy in frequency and phase correction compared to existing methods.

The paper creates a brain atlas of the dwarf cuttlefish using MRI, deep learning, and histology, identifying 32 brain regions and providing an interactive web tool for data access.

This paper introduces DeepSPEC, a CNN-based method for frequency-and-phase correction of MRS data, showing improved accuracy and robustness to noise compared to MLP and mSR methods.

The paper uses MRI and TBM to show that tau pathology spread in a mouse model correlates with brain volume loss but not neuronal loss in specific regions.