Clara L. Poupault

Combining TCE therapy with IL-2 enhances TCE efficacy in aggressive small-cell lung cancer and melanoma models with low target antigen density through T cell clonal replacement and CD8+ effector T cell differentiation.

The paper shows T cells promote SCLC growth through an IL-6/CD74 axis, and IL-6 blockade enhances immunotherapy effectiveness in SCLC.

This study identifies that combining DHODH inhibition with BCL-XL targeting synergistically induces apoptosis in pancreatic cancer, offering a new combination therapy strategy.

The paper investigates how dietary lipid manipulations affect the Drosophila eye proteome and identifies lipid-responsive proteins involved in muscle function and stress responses.

The paper quantifies the proteome of the Drosophila melanogaster eye using GeLC-MS/MS and provides a resource for further studies.