José Miguel Escandell

This study uses CRISPR-Cas9 to perturb myeloid lectins in macrophages, revealing target-specific transcriptional changes and immunometabolic reprogramming in tumor-associated macrophages.

This study develops a serum-free process for generating producer cell lines for scalable and efficient rAAV production, achieving productivity and quality comparable to serum-based methods.

This study shows that Pot1 in fission yeast is essential for telomere DNA replication by recruiting the Stn1-Ten1 complex and Pol-primase, preventing ssDNA accumulation and telomere loss.