Ubiquitin Proteasome System Components, RAD23A and USP13, Modulate TDP-43 Solubility and Neuronal Toxicity
Casey Dalton, Jelena Mojsilovic‐Petrovic, Nathaniel Safren, Carley Snoznik, Kamil K. Gebis, Yizhi Wang, Alexandra B. Sutter, Todd Lamitina, Jeffrey N. Savas, Robert Gordon Kalb
This study identifies RAD23A and USP13 as modifier genes that enhance TDP-43 solubility and reduce neuronal toxicity in ALS models.
Journal of Neuroscience · Dec 10, 2025Peer-reviewedNeuroscience