Jelena Mojsilovic‐Petrovic

This study identifies RAD23A and USP13 as modifier genes that enhance TDP-43 solubility and reduce neuronal toxicity in ALS models.

This paper identifies CSPG4 as a mediator of arginine-rich DPR uptake and cell-to-cell transmission, suggesting it as a therapeutic target for ALS/FTD.

This paper identifies SPOP as a conserved regulator of C9orf72 dipeptide toxicity in C. elegans and mammalian neurons, showing SPOP inhibition protects against toxicity.

The paper identifies metabolic reprogramming in neurons of familial ALS models, showing impaired glycolytic flux with maintained citric acid cycle activity and normal ATP levels.