Jakub Pospíšil

Sublethal stress from polypharmacy modulates scavenging function and fenestrations in mouse liver sinusoidal endothelial cells

This study examines how polypharmacy affects liver sinusoidal endothelial cells, showing drug- and concentration-dependent changes in fenestrations and endocytosis.

Offsetting ROS-mediated arrest of endothelial fenestration dynamics permits long-term optical super-resolution- and AFM-imaging

The paper identifies ROS as a cause of fenestration arrest in LSECs during imaging and proposes a strategy to preserve dynamics for long-term super-resolution and AFM imaging.