Author

Milena Deptuła

Gdańsk Medical UniversityORCID 0000-0003-4875-770XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Anna KosteckaiD· 1 shared Arkadiusz PiotrowskiiD· 1 shared David K. CrossmaniD· 1 shared Jakub Baczyński-KelleriD· 1 shared Justyna SawickaiD· 1 shared Magdalena KoczkowskaiD· 1 shared Maria DzierżyńskaiD· 1 shared Michael R. CrowleyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Anna KosteckaORCID

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1 paper

Recent·Most cited

Development of a small-molecule epigenetic regenerative therapy. Subcutaneous administration of alginate formulations with high loads of zebularine and retinoic acid promotes tissue growth, vascularization and innervation and induces extensive epigenetic repatterning

Paulina Słonimska, Jakub Baczyński-Keller, Rafał Płatek, Milena Deptuła, Maria Dzierżyńska, Justyna Sawicka, Oliwia Król, Paweł Sosnowski, Magdalena Koczkowska, Anna Kostecka, David K. Crossman, Michael R. Crowley, Piotr Sass, Ryszard Tomasz Smolenski, Piotr Mariusz Skowron, , Paweł Sachadyn

This study develops alginate-based formulations of zebularine and retinoic acid for subcutaneous administration, promoting tissue regeneration and epigenetic changes in mice without adverse effects.

Scientific Reports · Oct 29, 2025Peer-reviewedBioengineering