Natalie K. Goto

This study uses NMR peak intensity analysis to identify functional dynamics hotspots in proteins, showing that specific structural flexibility correlates with function in red fluorescent proteins.

TReSR is a computational method to redesign DNA sequences encoding tandem repeats to improve PCR compatibility, enabling the construction of TR-containing proteins.

This study identifies a transient amphipathic helix in PCSK9's prodomain that facilitates LDL binding, with mutations affecting this structure altering binding affinity and activity.