Zhaoyue Zhang

This study identifies a distinct metabolomic signature in Drosophila under chronic social isolation, linking it to changes in sleep, feeding, and metabolism.

This study shows that macronutrient composition and genetic background influence the response to a ketogenic diet in mice, with B6J mice losing weight on a low-protein KD due to increased GDF15 and LCN2 levels.

The paper identifies mTOR activation in POMC neurons as a key mechanism causing leptin resistance in diet-induced obese mice.

This study quantifies metabolic fluxes of circulating metabolites in mice using isotope tracing and mass spectrometry to identify major metabolic cycles and their tissue-specific contributions.