Sandosh Padmanabhan

This paper critiques a study linking L-type calcium channel blockers to heart failure, identifying flaws in methodology, data interpretation, and mathematical analysis.

The paper identifies SNPs with sex-specific effects on lung function traits using UK Biobank data, finding a significant interaction at rs7697189 near HHIP.

The paper examines genetic and shared couple environmental factors influencing smoking and alcohol use in the UK population using family and couple data.

This study identifies 210 genetic loci associated with the PR interval through multi-ancestry GWAS, highlighting their role in cardiac conduction and cardiovascular disease.

This study identifies a genome-wide significant association between a variant in the KCND3 gene and early repolarization pattern on ECG, suggesting a genetic basis for this trait.

This study investigates genetic associations between major depression and cardio-metabolic traits, finding shared genetic aetiology regardless of depression onset age.

The paper assesses if genetic risk for atrial fibrillation explains cardioembolic stroke risk using genome-wide data from the Stroke Genetics Network.

This study identifies 13 novel genetic loci associated with endometriosis through a large GWAS meta-analysis and finds genetic links to other pain-related conditions.

This paper introduces SAPPHO methods to detect pleiotropy in GWAS by modeling shared patterns of genetic associations, finding 16 additional and 124 novel loci in meta-analysis.

The paper investigates the genetic and environmental contributions to stressful life events and their overlap with depression and neuroticism using a large family-based sample.

This study identifies 47 novel genetic loci associated with PR interval through genome-wide association meta-analysis across multiple populations.

This study investigates shared genetic architecture between subcortical brain volumes and MDD using GWAS data from multiple cohorts, finding a non-significant positive genetic correlation for hippocampal volume.

This study conducts a GWAS of alcohol consumption in UK Biobank, identifying 8 loci, including novel associations, and reports genetic overlaps with schizophrenia, HDL cholesterol, smoking, and anthropometric traits.

This study identifies shared genetic and couple-associated environmental factors contributing to both clinical and self-declared depression risks.