Hong Zhang

This paper identifies maternal-effect mutants in zebrafish that reveal molecular mechanisms controlling the oocyte-to-egg transition, focusing on yolk globule formation and protein processing.

The paper identifies four zebrafish maternal-effect mutants affecting egg-to-embryo transition processes and discovers a novel conserved gene, krang, involved in cortical granule function during egg activation.

This study identifies RXRA as a therapeutic target for doxorubicin-induced cardiomyopathy in zebrafish by showing its endothelial-specific function and response to FDA-approved agonists.