Hong Zhang

Long-range transport of biomolecular condensates by Marangoni effect

The paper identifies the Marangoni effect as a mechanism for intracellular transport of biomolecular condensates using C. elegans zygotes and in vitro experiments.

Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

This study identifies HSD11B1 as a direct target of magnesium isoglycyrrhizinate, revealing its therapeutic mechanism in alcohol-associated liver disease through the HSD11B1-SREBP2-IDI1 signaling axis.

Long-term Locus Coeruleus Stimulation Exacerbates Tau Pathology in PS19 Mice

This study shows that long-term locus coeruleus stimulation worsens memory, synaptic plasticity, and Tau pathology in PS19 mice.

Endogenously generated Dutch-type Aβ nonfibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation

This study shows that nonfibrillar Aβ aggregates in APPE693Q mice disrupt presynaptic function without causing inflammation.

Oxytocin restores context-specific hyperaltruistic preference through moral framing

This study investigates how oxytocin affects hyperaltruistic preferences in moral decision-making contexts, showing it restores context-dependent preferences by altering subjective harm framing.

Therapeutic Potential of a Tectorigenin Derivative (TED) in Herpetic Stromal Keratitis: Antiviral and lmmunomodulatory Mechanisms

This study evaluates TED's anti-HSV-1 effects and therapeutic efficacy in HSK, finding it reduces viral loads and modulates immune responses through TLR pathway inhibition and immune cell regulation.

Germinated brown rice research: bibliometric analysis of progress, hotspots and trends

This paper uses bibliometric analysis to examine global research trends and hotspots in germinated brown rice from 2003 to 2023, highlighting China's leadership and key research topics.

Adenosine triggers early astrocyte reactivity that provokes microglial activation and drives the pathogenesis of sepsis-associated encephalopathy

This study shows that adenosine triggers early astrocyte reactivity in sepsis, leading to microglial activation and SAE pathogenesis.

ECSIT prevents Alzheimer's disease pathology by regulating neuronal mitochondrial ROS and mitophagy

This study shows that ECSIT regulates neuronal mitochondrial ROS and mitophagy, and its reduction contributes to Alzheimer's disease pathology.