Author

Hirotaka Watanabe

Keio UniversityORCID 0000-0003-4963-260XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Hideyuki OkanoiD· 2 shared Aika Akahori· 1 shared Akinori MiyashitaiD· 1 shared Hayato Etani· 1 shared Iki Sonn· 1 shared Jumpei OmiiD· 1 shared Junken AokiiD· 1 shared Kagistia Hana UtamiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Hideyuki OkanoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 10, 2026

Ropinirole hydrochloride mitigates oxidative stress and neuroinflammation via the PI3K-mTOR pathway in TDP-43 hiPSC-derived microglial-like cells

Kagistia Hana Utami, Tatsuya Kozaki, Satoru Morimoto…·Hideyuki Okano

This study shows ropinirole hydrochloride reduces oxidative stress and neuroinflammation in TDP-43 mutant microglial-like cells by modulating the PI3K-mTOR pathway.

DOI 10.64898/2026.03.07.710283

humanstatistical model

𝕏 PostBluesky

NeuroscienceAlzheimer s Research & TherapyPeer-reviewedNov 20, 2025

Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils

Hayato Etani, Sho Takatori, Wenbo Wang…·Taisuke Tomita

This study identifies GPR34 as a regulator of microglial amyloid β fibril uptake, showing that its agonist enhances fibril clearance and that its expression declines with age and AD progression.

15 citationstop 4%

humanmouse

𝕏 PostBluesky