Author

Tatsuya Kozaki

Agency for Science, Technology and ResearchORCID 0000-0003-4997-3199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Florent GinhouxiD· 2 shared Arpiar B. SaundersiD· 1 shared Christopher LeeiD· 1 shared Farah TasnimiD· 1 shared Gregory ChiniD· 1 shared Hanry YuiD· 1 shared Hervé BourhyiD· 1 shared Hideyuki OkanoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

Florent GinhouxORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 10, 2026

Ropinirole hydrochloride mitigates oxidative stress and neuroinflammation via the PI3K-mTOR pathway in TDP-43 hiPSC-derived microglial-like cells

Kagistia Hana Utami, Tatsuya Kozaki, Satoru Morimoto…·Hideyuki Okano

This study shows ropinirole hydrochloride reduces oxidative stress and neuroinflammation in TDP-43 mutant microglial-like cells by modulating the PI3K-mTOR pathway.

DOI 10.64898/2026.03.07.710283

humanstatistical model

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ImmunologybioRxivAug 26, 2025

Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation

Christopher Lee, Farah Tasnim, Xiaozhong Huang…·Florent Ginhoux

This study shows that co-culturing iPSC-derived macrophages with hepatocytes enhances macrophage maturation and hepatocyte function through direct cell-cell contact.

1 citation

humanscRNA-seq

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NeuroscienceCell ReportsPeer-reviewedAug 25, 2025

Human brain cell types shape host-rabies virus transcriptional interactions revealing a preexisting pro-viral astrocyte subpopulation

Lena Feige, Karl Young, Juan‐Pablo Cerapio…·Arpiar B. Saunders

The paper investigates how rabies virus interacts with different human brain cell types, identifying a pro-viral astrocyte subpopulation that enhances viral transcription.

4 citations

humanscRNA-seq

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