Author

Anna Yoney

Rockefeller UniversityORCID 0000-0003-4988-9237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:statistical model· 2 Research Focus:differential expression· 1

Frequent Co-Authors

Ali H. BrivanlouiD· 5 shared Eric D. SiggiaiD· 4 shared Fred EtociD· 4 shared Albert Ruzo· 3 shared Jakob Johannes MetzgeriD· 3 shared Shu LiiD· 3 shared Iain MartyniD· 2 shared Tien Phan-Everson· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersDevelopmental Biology

Ali H. BrivanlouORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

Anna Yoney, Lu Bai, Ali H. Brivanlou, Eric D. Siggia

The paper identifies EOMES as a key mediator of WNT priming in human embryonic stem cells, enabling subsequent Activin-induced mesendodermal differentiation.

Development · Jul 11, 2022Peer-reviewedDevelopmental Biology

Huntingtin CAG expansion impairs germ layer patterning in synthetic human gastruloids through polarity defects.

Szilvia Galgoczi, Albert Ruzo, Christian Markopoulos, Anna Yoney, Tien Phan-Everson, Shu Li, Tomomi Haremaki, Jakob Johannes Metzger, Fred Etoc, Ali H. Brivanlou

This study shows that HTT-CAG expansion in human gastruloids causes ectodermal compartment reduction and altered TGFβ signaling due to polarity defects, indicating early developmental HD effects.

Development · Oct 1, 2021Peer-reviewedDevelopmental Biology

Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport

Tien Phan-Everson, Fred Etoc, Shu Li, Samuel Khodursky, Anna Yoney, Ali H. Brivanlou, Eric D. Siggia

The paper shows that NOGGIN and BMP4 are secreted into opposite extracellular spaces in human epiblasts, with NOGGIN inhibiting BMP4 through apical-to-basal transcytosis.

Developmental Cell · May 27, 2021Peer-reviewedDevelopmental Biology

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids

Anna Yoney, Fred Etoc, Albert Ruzo, Jakob Johannes Metzger, Iain Martyn, Shu Li, Christoph Kirst, Thomas Carroll, Eric D. Siggia, Ali H. Brivanlou

The paper shows that WNT signaling memory enables ACTIVIN to act as a morphogen in human gastruloids by allowing graded responses to ACTIVIN without altering SMAD2 dynamics.

eLife · Oct 12, 2018Peer-reviewedDevelopmental Biology

Molecular mechanism of symmetry breaking in a 3D model of a human epiblast

Mijo Simunovic, Jakob Johannes Metzger, Fred Etoc, Anna Yoney, Albert Ruzo, Iain Martyn, Gist F. Croft, Ali H. Brivanlou, Eric D. Siggia

The paper generates a 3D human epiblast model to study axial symmetry breaking, showing BMP4 induces symmetry breaking through WNT3 and DKK1.

bioRxiv · May 29, 2018 · PreprintDevelopmental Biology