Author

Sweta Karan

University of California, IrvineORCID 0000-0003-4989-313XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Lbachir BenMohamediD· 4 shared Swayam PrakashiD· 4 shared Aziz Alami ChentoufiiD· 3 shared Afshana QuadiriiD· 2 shared Chhaya Maurya· 2 shared Hawa VahediD· 2 shared Anthony B. Nesburn· 1 shared Delia F. TifreaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersImmunology

Lbachir BenMohamedORCID

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 2, 2026

A Tissue-Targeted Immunotherapy Protects Against Recurrent Ocular Herpes Infection and Disease, and Alleviates the Associated Cognitive, Behavioral, and Social Deficits in a 'Humanized' HLA Transgenic Mouse Model of UVB-Induced Reactivation

Sweta Karan, Swayam Prakash, Aziz Alami Chentoufi…·Lbachir BenMohamed

This paper demonstrates that a PPK immunotherapy reduces HSV-1 reactivation and associated neurobehavioral deficits in a humanized mouse model.

DOI 10.64898/2026.09.27.754856

mouseexperimental assay

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ImmunologybioRxivPreprintSep 20, 2026

Tissue-Resident and Effector-Memory Lymphocyte Recruitment to the Ocular Mucosa Requires CCL28/CCR10 Signaling During Recurrent HSV-1 Infection

Sweta Karan, Swayam Prakash, Chhaya Maurya…·Lbachir BenMohamed

This study shows that CCL28/CCR10 signaling is essential for recruiting protective lymphocytes to the ocular mucosa during recurrent HSV-1 infection, reducing viral burden and ocular pathology.

DOI 10.64898/2026.09.14.751393

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 18, 2025

CXCL13/CXCR5 Chemokine Axis Promotes CXCR5+CD19+ B-Cell and Follicular/Effector CXCR5+CD4+ T-Cell Responses in the Lungs Associated with Protection from Severe and Fatal COVID-19 Following Infection with Pathogenic SARS-CoV-2 Delta Variant

Hawa Vahed, Aziz Alami Chentoufi, Swayam Prakash…·Lbachir BenMohamed

This study shows that CXCL13 deficiency in mice worsens SARS-CoV-2 infection, with higher viral load, lung damage, and reduced B and T cell responses.

DOI 10.1101/2025.04.18.649623

mouseexperimental assay

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ImmunologyJournal of VirologyPeer-reviewedApr 10, 2025

Tissue-Targeted Prime/Pull/Keep Therapeutic Herpes Simplex Virus Vaccine Protect Against Recurrent Ocular Herpes Diseases in HLA-A*0201 Transgenic Rabbits

Aziz Alami Chentoufi, Swayam Prakash, Hawa Vahed…·Lbachir BenMohamed

This study tests a prime/pull/keep HSV-1 vaccine in HLA-A*0201 transgenic rabbits, showing it reduces corneal herpes infection by mobilizing and retaining CD8+ T cells in infected tissues.

8 citationstop 4%

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