Author

Philippa I P Holzapfel

Utrecht UniversityORCID 0009-0000-0160-3450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Bart W. BardoeliD· 1 shared Carla J. C. de HaasiD· 1 shared Dani A. C. HeesterbeekiD· 1 shared Fabian HauseriD· 1 shared Jaroslaw JacakiD· 1 shared Marije van 't WoutiD· 1 shared Suzan H. M. RooijakkersiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Bart W. BardoelORCID

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1 paper

Recent·Most cited

MicrobiologyEMBO ReportsPeer-reviewedDec 8, 2025

Bactericidal Membrane Attack Complex formation initiates at the new pole of E. coli

Marije van 't Wout, Fabian Hauser, Philippa I P Holzapfel…·Dani A. C. Heesterbeek

The paper tracks MAC pore localization on E. coli and finds that MAC deposition starts at the new bacterial pole, leading to inner membrane damage and halting division.

2 citations

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